Laboratory: Neurophysiology # 1

Group Leader: Paolo Calabresi M.D., Ph.D.

• n.2 complete set-up for intracellular electrophysiological (electrods "sharp") recording from tissue slices.

• n.2 complete set-up for whole-cell patch-clamp electrophysiological recording from tissue slices with infra-red and microfluorimetry analysis.

1. Calabresi P, Gubellini P, Picconi B, Centonze D, Pisani A, Bonsi P, Greengard P, Hipskind RA, Borrelli E, and Bernardi G. Inhibition of mitochondrial complex II induces a long-term potentiation of NMDA-mediated synaptic excitation in the striatum requiring endogenous dopamine. J Neurosci. 2001, 21(14):5110-20.
2. Centonze D, Pisani A, Bonsi P, Giacomini P, Bernardi G, Calabresi P. Stimulation of Nitric Oxide-cGMP Pathway Excites Striatal Cholinergic Interneurons via Protein Kinase G Activation. J Neurosci. 2001, 21(4):1393-1400.
3. Calabresi P, Gubellini P, Centonze D, Picconi B, Bernardi G, Chergui K, Svenningsson P, Fienberg AA, Greengard P. Dopamine and cAMP-regulated phosphoprotein 32 kDa controls both striatal long-term depression and long-term potentiation, opposing forms of synaptic plasticity. J Neurosci. 2000, 20(22):8443-51.
4. Calabresi P, Centonze D, Bernardi G. Electrophysiology of dopamine in normal and denervated striatal neurons. Trends Neurosci. 2000, 23(10 Suppl):S57-63.
5. Calabresi P, Centonze D, Gubellini P, Pisani A, Bernardi G. Acetylcholine-mediated modulation of striatal function. Trends Neurosci. 2000, 23(3):120-6.

   

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